Pox when you’re pregnant, it dangerous?

March 17, 2010 at 1:26 pm (Pregnancy) (, , , , , , , , )

Pregnant women are particularly vulnerable to bacterial infections, viruses, and parasites. This is due to physiological, the immune system of pregnant women declined. Infection can be bad for the mother and fetus. One of the infections that often concern is smallpox.

New fetal immune system is formed at 12 weeks of gestation. At 26 weeks of gestation, the fetal immune system is almost the same as her mother. At birth, the baby is still getting antibodies from the mother. Slowly, two months later antibodies in infants decreased. Condition of pregnant women vulnerable to it should be extra attention to their own health in order to avoid infection, one of smallpox.

Small risks
Ever pregnant women colleagues who are worried infected with smallpox. “Afraid of Nothing with my baby,” she says. Smallpox is intended chickenpox or varicella. The stranger called chickenpox.

Smallpox is caused by varicella zoster virus (VZV) or also called human herpes virus-3 (HHV-3). This virus DNA into the latent virus that lives in the ganglion (ganglion) the back after the primary infection.

Approximately 80-90 percent of adults have become infected with smallpox, and thus have immunity. In those who had been exposed, the virus is not completely lost from the body. Virus hiding in a particular nerve, and one day be active again in the form of herpes zoster infection

If a new primary infection occurs during adulthood, the clinical disease will be more severe arise. This includes when in pregnant women and those with complications of the disease.

Chickenpox infection in the first trimester of pregnancy can cause birth defects such as inflammation in the retina of the eye (korioretinitis), did not develop a large part of the brain (cerebral cortex atrophy), enlarged kidney (hydronephrosis), and abnormalities in bone and skin.

If the infection attacks the pregnancy at the age of less than 13 weeks, the possibility of birth defects that occurred about 0.2 percent. While the infections occurred in 13-20 weeks of gestation, the infection increased to 0,4-2 percent. However, if infection occurs after 20 weeks of gestation, generally does not happen abnormalities. Please note that the varicella virus incubation period is less than two weeks.

Vaccines VZIG
If delivery occurs before the incubation period or just the time of delivery, the baby will be infected. And can cause defects in the gut and central nervous system, since antibodies in the mother’s body has not been established. Therefore, babies born to a special immunization shots as a precaution.

Immune substances recommended by the CDC and Prevention in 1996 as an act of prevention of smallpox is varicella zoster immunoglobulin (VZIG). Dose is 125 U/10 kg body weight, maximum 5 vials for pre-or post-infection.

Yet not every pregnant woman needs an injection of vaccine. Simply ask medical history, whether the subject had chickenpox or not. When you’ve got, of course already have antibodies.

While mothers are not exposed to smallpox, a high risk of contracting chickenpox. Especially if the neighborhood where he lived were infected with smallpox outbreaks. Mother is a priority to get the vaccine VZIG.

Vaccines can be given to pregnant women before delivery and newborn. The principle is given VZIG within the period of 96 hours after exposure to smallpox infection.
In infants, the injection was given 5 days before and after delivery with VZIG vaccine or zoster immunoglobulin (zig). Giving this vaccine in infants is still possible keep 30-40 percent of babies infected with the virus.

In other words, this vaccine can protect 60-70 percent of infected infants from the risk of complications and death. There is also another vaccine, which is varivax live virus vaccine. It’s just not direkomendaskan vaccine for pregnant women.

Avoid direct contact
Another way of prevention, ie avoiding direct contact with those who are sick. Transmission can occur from 48 hours before the first rash until 5 days later. Chicken pox can be spread through breathing air, direct contact with the liquid rash, and contact with infected items such as a rash of fluid sheets, blankets, and towels.

Papules and vesicles that have not also contain a lot of dry and potentially pass the virus. Chickenpox in pregnancy with the virus in the blood (viremia), can spread through the placenta to the fetus.

Given the highly vulnerable to infection, is important for pregnant women to maintain their health, among others, by always eating nutritious food.
When smallpox infection when pregnant, do not be too worried. The risk of birth defects is not too large, but still must be vigilant. Immediately consult a gynecologist in order to obtain information and appropriate treatment.
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